The Greenberg Lab Gene Database is designed to support the manuscript “Single-Cell Analysis of Experience-Dependent Cell States in Mouse Visual Cortex.” It provides researchers with access to gene expression data related to neuronal activity and experience-dependent transcriptional changes in the mouse visual cortex.
- Data Accessibility: Users can input specific gene names to retrieve normalized expression data across various cell types under different light exposure conditions.
- Experimental Conditions: The database includes data from experiments where mice were dark-reared for a week, followed by one of three stimulation conditions: no light exposure, one hour of light exposure, or four hours of light exposure.
- Analytical Tools: Provides visual representations of gene expression levels, including mean normalized expression and 95% confidence intervals, facilitating the analysis of activity-dependent gene regulation.
- Research Support: Serves as a supplementary resource for understanding how sensory experiences influence gene expression and neural circuit development in the visual cortex.
Through these features, the Greenberg Lab Gene Database offers valuable insights into the molecular mechanisms underlying experience-dependent neuronal plasticity.